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INVESTIGATION OF ANTIOXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITY OF BARLERIA TERMINALIS IN HIGH FAT DIET EXPERIMENTAL ANIMALS.

Authors

  • Samiksha Dilip Yende

    Vidyabharati College of Pharmacy, Amravati
    Author

  • Dr. Vivek V. Paithankar

    Author

  • Dr. Anjali Wankhade

    Translator
Keywords:
High Fat Diet (HFD), Antioxidant Activity, Antihyperlipidemic Activity, Free Radicals, Hepatoprotective Activity, Nephroprotective Activity
Abstract

The present study was aimed to investigate the antioxidant and antihyperlipidemic activity of Barleria terminalis in High Fat Diet (HFD) induced hyperlipidemic rats. Phytochemical screening revealed the presence of flavonoids, phenols, glycosides, tannins, saponins, and steroids. Treatment with Barleria terminalis extract significantly reduced total cholesterol, triglycerides, LDL, and VLDL while increasing HDL levels. The extract also improved antioxidant parameters and showed protective effects in histopathological studies. The study concluded that Barleria terminalis possesses significant antioxidant and antihyperlipidemic activity and may be useful in the management of hyperlipidemia.

Published
2026-06-06
Issue
Vol. 2 No. 1 (2026): volume-2-2026 Issue-01
Section
Articles
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Article published in this journal are licensed under creative commons Attribution 4.0 International License ( CC BY 4.0)